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Research Confirms, Sugar Feeds Cancer

Research Confirms, Sugar Feeds Cancer

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sugar_cancer(OrganicJar) Researchers at Huntsman Cancer Institute at the University of Utah have uncovered new information that sugar “feeds” tumors. The findings may also have implications for other diseases such as diabetes. The research is published in the journal Proceedings of the National Academy of Sciences.

“It’s been known since 1923 that tumor cells use a lot more glucose than normal cells. Our research helps show how this process takes place, and how it might be stopped to control tumor growth,” says Don Ayer, Ph.D., a Huntsman Cancer Institute investigator and professor in the Department of Oncological Sciences at the University of Utah.

During both normal and cancerous cell growth, a cellular process takes place that involves both glucose (sugar) and glutamine (an amino acid).


Glucose and glutamine are both essential for cell growth, and it was long assumed they operated independently, but Ayer’s research shows they are inter-dependent. He discovered that by restricting glutamine availability, glucose utilization is also stopped. “Essentially, if you don’t have glutamine, the cell is short circuited due to a lack of glucose, which halts the growth of the tumor cell” Ayer says.

The research, spearheaded by Mohan Kaadige, Ph.D., a postdoctoral fellow in Ayer’s lab, focused on MondoA, a protein that is responsible for turning genes on and off. In the presence of glutamine, MondoA blocks the expression of a gene called TXNIP. TXNIP is thought to be a tumor suppressor, but when it’s blocked by MondoA , it allows cells to take up glucose, which in turn drives tumor growth. Ayer’s research could lead to new drugs that would target glutamine utilization, or target MondoA or TXNIP.

Ayer says the next step in his research is to develop animal models to test his ideas about how MondoA and TXNIP control cell growth. “If we can understand that, we can break the cycle of glucose utilization which could be beneficial in the treatment of cancer,” Ayer says.

My Thoughts

I think its important to remember that all of us have cancer right now, but our immune system fights it off. That’s why diet is so important, we all must keep our immune system running at 100%. I think we can also agree that we know sugar isn’t good for us, our tongue loves it, but our body doesn’t. So why would we consume something that ‘feeds’ the very thing most of us fear the most?

Where are we getting all this sugar? If I had to guess it’d be soda pop. Think about this…if sugar is proven to feed cancer, and the number of Americans with cancer increases every year, could there be a link regarding soda and cancer? Here are some scary statistics and something to think about.

  • Soda pop is basically liquid sugar .
  • More than a quarter of all drinks consumed in the United States are soda.
  • Americans drink an average of 1.6 cans of soda pop every day.
  • 80% of schools have soda vending machines.
  • 56% of 8-year-olds down soft drinks daily, and 1/3 of teenagers drink at least 3 cans of soda pop per day.
  • Carbonated soda pop provides more added sugar in a typical 2-year-old toddler’s diet than cookies, candies and ice cream combined.

Leave a Comment and Tell Us Your Thoughts on Soda Pop?

Source: Proceedings of the National Academy of Sciences (research paper) sciencedaily.com

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  1. I agree with you. But you are making quite a leap . Circumstanial.

  2. I think what the paper is referring to is the use of glucose during the formation of cellular energy (ATP) in the Krebs cycle. All cells require glucose to carry this out. I think the point would be to target the cancer cells and limit their ability to utilize glutamine thereby reducing the ability to grow by shutting down the creation of ATP. I agree with you that too much refined sugar in the diet is a bad idea, but I don’t really think that is related to this research since all cells breakdown metabolites into glucose to create energy.

  3. Great article. I completely agree that we have to let manufacturers know that sugar –in all its harmful forms, including corn syrup, etc.— shouldn’t be added to so many products. Today, I was shopping at a local health food store, and I noticed some products hawked as “healthy” that contained sugar. The sad thing is that people become addicted to it. If you don’t drink soda, eat sugary desserts, etc., then sugar actually has an almost unpleasant taste.

    Linda

  4. Yeah the article does focus on glucose, and ‘my thoughts’ were a bit of a stretch but that’s just what was going though my mind when I was writing the article so I wanted to share it. Thank you for your thoughts. Cheers! – Jason

  5. While I appreciate your passion for what you do, I agree with the others in regard to the confusion of substances per your thoughts verses the article. Better luck next time.

  6. There are other sugars to consider. Sucrose lowers immunity for several hours after ingestion. Also stops human growth hormone production. There are polysaccharide sugars(sour/bitter)that support correct communication between the cells and the immune system. Search glyconutrients. In mother’s milk,healthy bodies make em, but after ab’t age 40,deficiency symptoms arise. Sucrose contributes to acid PH also associated w/cancer. Glutamine is used to make glutathione, so can’t be the enemy. Glyco-sugars combine w/amino acids @ fats to build the structures on the cell surface that facilitates this communication so your body gets the messages. Natural health nut since 1971,triple negative breast cancer survivor since 2006. Can you name all the “healthy” people who have gotten cancer? long list. Copper, iron, hormones,especially stress hormones, also can feed cancer. Cancer cells have intelligence and can use your own immune system to post guards at the cell wall so your own immune system can’t attack. Start googling the worldwide research on polysaccharides and cancer. There’re 8 sugars that must be in place together for optimal benefit. Google just one of them, amazing research: mannose, fucose, xylose, sialic acid aka n-acetyl neurominic acid, glucose, n-acetyl glucosamine, n-acetyl galactosamine, galactose. Open a new world…
    Brynda

  7. I think sugar is just fine, if its not in EVERYTHING in the dang grocery store. It should be in tea and some cereals, but why is it in bread, vegetables, dinners, pasta, pizza, fruit juice, and sometimes even things like cheese or fish sticks.

  8. agreed, ‘my thoughts’ were a tangent on the article. I was aware of this when I was writing it and I could have phrased it better. Life is all about learning and I don’t claim to know everything so I appreciate all of your comments, they help me grow and improve. cheers! :) – Jason

  9. Cancer is a fungus…?

  10. We always assume that sugar comes from ‘added sugars’ and forget the very high sugar carbs (breads/pasta) fruit juices and the un-digestible sugars in dairy products…(see highest dairy eating countries…see highest hormonal cancers stats.
    Thos are MY thoughts and soda? well that just seems a bit obvious…

  11. Also we should remember that ALL starches break down into sugars in our system. Pop, breads, potatoes, fruites, starchy veg, etc! Yes, some break down slower, but the fact is that a high-carbohydrate diet will always be unnatural for our bodies.

    Anyone interested in some sound scientific evidence for this should watch this lecture. It blew my mind! It is about how carbohydrates are used by our bodies.

    http://www.dhslides.org/mgr/mgr060509f/f.htm

    Keep up the sending out the great information, sharing knowledge is power! ;)

  12. Disease feeds on white refined addicting sugar that is definitely a fact – it breeds inflammation internally & taxes the liver and immune system. We would have exponentially lower incidence of our major diseases in the US and the world if people would eliminate all refined sugar from their diet, and YES this is entirely possible – as whole foods nutritionists we have done this for years & we never get sick now with even a cold…hmmm, I wonder why. ;-) That and the power-packed combo of adding a ton of organic healthy plant foods to our daily health routine.

  13. So I wonder what about diet soda? Aspartame is no good either, but is the link b/w cancer and aspartame because it’s a sugar substitute?

  14. Hey Jason,

    The sugar problem is much, much worse than the soda pop issue you propose. Processed sugar is present in nearly everything on the shelves, from bread, toothpaste and mouthwash to cooked meats, canned vegetables/pulses and beer and wine. Amazingly, with obesity and diabetes earmarked as the epidemics of the future, the discussion focuses on carbs and fats while sucrose/saccharose get off scot free. I have a sneaking suspicion that there’s corporate interests at stake here – after all, much of our Western wealth is (historically) based on the manufacture of sugar. The US market for high intensity sweeteners back in 1998 was already worth a staggering 1.5 billion bucks.

    It is important to distinguish processed (complex) sugars from natural (simple) sugars such as fructose present in honey, fruit and vegetables. Simple sugars metabolize more smoothly (i.e. without causing the blood sugar peaks associated with sucrose) and are ‘nature’s treat’. Complex sugars are corporate poison. While no statistics are available on the numbers of people suffering from glucose-intolerance (a metabolism disorder requiring a diet free from processed sugar), all manner of individual complaints may in fact be undiagnosed glucose-intolerance. Symptoms such as palpitations may result from the overproduction of insulin in response to a blood sugar peak. Other symptoms include regular headaches, general fatigue, palpitations, severe mood swings as well as an immediate and uncontrollable need to sleep deeply following the act of eating, weight loss, photo phobia, aching muscles (particularly from shoulder blade to neck) and joints to an extreme point of near-paralysis, chilblains (impaired circulation), persistent diarrhoea etc etc.

    There are considerable doubts about the long term health risks associated with sugar substitutes such as aspartam, malitol, sorbitol and in particular sucralose (sugar intensified 600 times by chlorine). By contrast, fruit sugar or fructose, cane sugar (also called demerara or golden sugar), corn syrup and agave syrup are less harmful, in the way they metabolize, than artificial sweeteners.

    Making informed choices about the way you live, what you eat and the effect your diet has on the environment (e.g. what are the effects of the chlorine in sucralose excreted in urine on marine life?) therefore involves reading each and every list of ingredients on each and every product you consume. Under EU regulations, fruit juice can only be called ‘juice’ if it is just that – 100% juice. All other drinks based on fruit but containing additives are called ‘drink’ or ‘nectar’. Healthy living means sugar-free living. So vote with your feet!

    P.S. I suffer from glucose-intolerance myself. In view of a general unwillingness on the part of Western physicians to take this condition seriously, or to classify the symptoms under various other headings such as hyperinsulinaemia or hypoglycemia, I have largely had to learn to live with it by trial and error. Research, too, is patchy. The above therefore does not pretend to be scientific truth but merely represents my own findings. If anyone has additional information for me, I’d be grateful. Equally, if anyone wants info from me, they are free to ask.

    Michaela

  15. yes, sugar is not a good thing, its the most addictive substance on earth.

  16. i know sugar isn’t the greatest for us. i’m not a biology wiz but i was wondering doesn’t our body need glucose (sugar) in order to produce ATP? so how much is too much and how do you know?

  17. While sugar does in fact feed cancer, inflammation is at the root of all disease.

  18. The sale of "Soft Drinks" at our public schools should be band. This product is one of the leading contributors to the poor state of Health occuring amoung our Nation's youth.

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